Phosphorylated Tau 217 (p-Tau 217) (CLIA)

 Product Description  

Phosphorylated Tau 217 (p-Tau 217) (CLIA) Kit provides a rapid, automated method for quantitative measurement of p-Tau 217, performed on a fully automated chemiluminescence immunoassay analyzer for reliable biomarker quantification in research applications.

The kit employs a double-antibody sandwich format. Monoclonal anti-p-Tau 217 antibodies coated onto magnetic particles serve as capture antibodies, while acridinium ester-labeled monoclonal anti-p-Tau 217 antibodies function as detection antibodies. Upon immunoreaction, antibody-antigen-antibody complexes are formed; addition of pre-trigger and trigger solutions induces chemiluminescent signal emission detected by the analyzer. The relative light units (RLUs) measured are directly proportional to the p-Tau217 concentration in the sample. The kit includes one reagent cartridge, two-level quality control materials, and three-level calibrators to support assay verification and calibration.

This product is intended for research use only and is not for use in diagnostic procedures.

 Features  

• Comprehensive Product Portfolio: Extensive biomarker menu enables flexible panel customization for diverse research needs across diverse sample types and multiple species

• Automated CLIA Workflow: Compatible with automated CLIA analyzers, enabling streamlined operation and rapid turnaround

• Proprietary High-affinity Antibodies: In-house developed monoclonal antibodies ensure sensitive and specific detection of p-Tau 217

• Lot-based Calibration: Reduces workflow burden and reagent consumption

 Performance  

• Linearity

Linear range: 0.50 – 50.00 pg/mL 

Linear correlation coefficient (r) ≥ 0.9900

• Limit of Blank (LoB)

Limit of Blank: ≤ 0.20 pg/mL

• Precision

Repeatability: CV ≤ 8.00% 

Intermediate precision: CV ≤ 15.00%

• Trueness

Relative deviation: [-15% , +15%]

 Components  

 Storage  

Store at 2–8 °C, protected from light, with a shelf life of 12 months.